Application of continuous lumbar drainage on traumatic subarachnoid hemorrhage
Abstract：ObjectiveTo investigate the effect of continuous lumbar drainage on traumatic subarachnoid hemorrhage.Methods Fifty patients with traumatic subarachnoid hemorrhage were divided the control group and observation group by random number table method, 25 cases in each group.The control group received lumbar puncture treatment, and the observation group was treated with continuous lumbar drainage.The parameters of cerebral blood volnine (CBV), cerebral blood flow (CBF), time to peak (TTP), mean transit time (MTT) in cerebral computed tomography (CT) perfusion imaging at different time points and the levels of endothelin-1 (ET-1), nitric oxidex (NO) in the cerebrospinal fluid were compared between the two groups.Results The parameters of CBV, CBF and NO in the observation group were obviously higher than those in the control group 7 and 14 days after treatment.The levels of TTP, MTT, ET-1 in the observation group were obviously lower than those in the control group 7 and 14 days after treatment (P=0.000).ConclusionTraumatic subarachnoid hemorrhage can induce cerebral vasospasm, and the continuous lumbar drainage can quickly remove the hemorrhagic cerebrospinal fluid to relieve the cerebral vasospasm, and improve cerebral blood perfusion and the prognosis of the patients.
Keywords：Continuous lumbar drainageTraumatic subarachnoid hemorrhageCerebrovascular spasmComputed tomography perfusion (CTP)Endothelin-1 (ET-1)Nitric oxide (NO)
Publication Date：2019-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 39-42 )