The clinical efficacy of Shuganjieyu capsules combined with quadruple therapy on helicobacter pylori positive gastric ulcer
ZHANG Yu
Abstract：Objective To evaluate the therapeutic effect of Shuganjieyu capsules combined with quadruple method on the treatment of helicobacter pylori(Hp) positive gastric ulcer. Methods 102 patients with positive gastric ulcer and Hp infection were selected as the research subjects. The patients were divided into two groups by random number table method: the quadruple group(using lansoprazole + colloidal pectin bismuth + clarithromycin + amoxicillin,n = 51) and the Shugan group(using Shuganjieyu capsules + the quadruple treatment,n = 51). Both of the two groups were treated for 6 weeks. The improvement of gastric function,the levels of gastrin(GAS) and motilin (MTL), and adverse reactions were compared between the two groups. Results The clinical curative effect of the Shugan group was better than that of the control group(P < 0. 01). The improvements of the gastrointestinal scores, and the levels of GAS and MTL in the Shugan group were better than those in the quadruple group 10 d,20 d and 30 d after treatment(P < 0. 05). Conclusion Shuganjieyu capsules can improve the clinical effect of quadruple treatment on Hp-positive gastric ulcer. It is safe and can improve the gastrointestinal function,reduce the secretion of GAS and MTL in the patients.
Keywords：Shuganjieyu capsuleQuadruple methodHelicobacter pyloriGastric ulcer
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 464-466 )