Diagnostic value of dual source CT for urate crystal deposition in gout patients in Beibu Gulf

doi:10.3969/j.issn.1674-3806.2018.05.10

Abstract：Objective To evaluate the diagnostic value of dual source CT for urate crystal deposition in gout patients in Beibu Gulf area. Methods Bilateral knee joints,ankle joints and bipedal dual energy CT scans were performed in 28 patients who were diagnosed with gout(the gout group). The control group consisted of 10 non-gout patients who were performed the same CT scans. The data were analyzed using gout software to record the presence of urate crystals and their distribution. The differences of urate deposition were compared between the two groups. The difference between the location of urate crystal deposition and the clinical evaluation was detected by dual source CT. Results Urate crystals were found in 124 cases in the gout group by dual energy CT scan,which was 2. 43 times higher than the lesions of the the clinical assessment(51 lesions). The most common site of the lesions was the first metatarsophalangeal joints(37. 9％), followed by the ankles(25. 8％) and the last was the knees(15. 3％). 13 patients suffered from bone destruction in varying degrees,16 cases were multiple joint destruction,and all the patients were accompanied by soft tissue swelling. No urate crystals were found in the control group. Conclusion Dual source CT scans can show urate crystal deposition qualitatively and quantitatively,which is of great clinical significance for early non-invasive diagnosis,prevention and treatment of gout patients in the Beibu Gulf region.