The expression of TGF-β1 and its clinical singnificances in female breast fibroadenoma
Abstract：Objective To study the expression of transforming growth factor -beta 1(TGF-β1) and it clini-cal singnificances in female breast fibroadenoma .Methods Twenty pairs of fresh tissue specimens including the tumor tissue and the matched normal tissue were collected from the female patients with breast fibroadenoma and were preserved in liquid nitrogen .The reverse transcription quantitative polymerase chain reaction ( RT-qPCR) was used to detect the levels of TGF-β1 mRNA l in the samples.Student′s t-test was used to analyze the data .Results The ex-pression of TGF-β1 mRNA was significantly elevated in the breast fibroadenoma tissues than that in the normal tissues ( P=0.004 ) .Conclusion As an important factor for the development of stroma , TGF-β1 is involved in the forma-tion process of fibroadenoma .
Keywords：BreastFibroadenomaTGF-β1
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 383-386 )