Exprse sion pat erns and significances of distant metastasis and prognosis of MiR-3182 innasopharygeal carci-noma
Abstract：Objective To investigate the expression patterns and the significances of distant metastasis and prognosis of MiR-3182 innasopharygeal carcinoma ( NPC) .Methods The expressions of MiR-3182 in 89 cases with nasopharygeal carcinoma were detected by real time RT-PCR.The relation between the expression and distant metas-tasis of NPC and its prognosis were analyzed .Results The expressions of MiR-3182 were found in all of the tissues of nasopharygeal carcinoma .The expression level of MiR-3182 in nasopharygeal carcinoma in the group with distant metastasis was significantly higher than that in the group without distant metastasis ( P<0.01 ) .The expression of MiR-3182 in the group with DFS <3 years was significantly higher than that in the group with DFS≥3 years ( P<0.01 ) .Conclusion MiR-3182 may play a key role in distant metastasis of nasopharygeal carcinoma and is associat -ed with poor prognosis .
Keywords：Nasopharygeal carcinomaMiR-3182Real timeRT-PCRDistant metastasis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 369-372 )