Effects of irbesartan, hydrochlorothiazide and amlodipine combined with metoprolol in the treatment of re-fractory hypertension
Abstract：Objective To study the effects of irbesartan, hydrochlorothiazide and amlodipine combined with metoprolol in the treatment of refractory hypertension.Methods Eighty patients with refractory hypertension were di-vided into the observation group(n=40) and the control group(n=40) according to the principle of voluntary.The control group received the treatment of irbesartan, hydrochlorothiazide and amlodipine.The treatment in the observa-tion group was the same as that in the control group except that metoprolol was added.Results In the observation group, 35 cases were markedly effective;5 cases effective;No cases ineffective.In the control group, 27 cases were effective;9 cases effective;4 cases ineffective.The clinical effect of the observation group was better than that of the control group(P<0.05).The incidence of adverse reactions in the observation group(0.00%) was significantly low-er than that in the control group(30.00%)(P<0.01).Conclusion Irbesartan in conjunction with hydrogen chlo-rine thiophene hydrochlorothiazide and amlodipine combined with metoprolol is safe and effective in the treatment of refractory hypertension.
Keywords：IrbesartanHydrochlorothiazideAmlodipineMetoprololRefractory hypertension
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 307-309 )