Diagnosis and surgical treatment of gastrointestinal stromal tumor:a report of 30 cases
HUANG Peng
WU He-shui
Abstract：Objective To explore the clinical characteristics,diagnosis and treatment of gastrointestinal stro-mal tumor( GIST) .Methods The clinical data of 30 patients with GIST who were admitted between June 2004 and June 2014 were analyzed retrospectively.Results In the 30 patients with GIST, the lesions were located in the stom-ach(14 cases), duodenum(2 cases), small intestine(10 cases), colon(2 cases) and rectum(2 cases).All the le-sions were identified by imaging examination.All patients underwent complete resections, including multiple organs resection(2 cases) and endoscopic resection(3 cases).After the operation, the diagnosis was confirmed by patholog-ical examination and immunohistochemistry.The results of immunohistochemistry demonstrated that tumor cells were positive for CD117 in 29 cases(96.7%), for CD34 in 22 cases(73.3%) and for DOG-1 in 28 cases(93.3%). Twenty-five patients were followed up postoperatively from 12 months to 10 years.During the follow-up period, 8 ca-ses died, recurrence or metastasis occurred in 8 cases, and 9 cases remained in a stable condition.Conclusion GIST shows untypical clinical features.Raising awareness of GIST, avoiding misdiagnosis, timely surgical resection and targeted therapy are the major measures for improving the prognosis of GIST.
Keywords：Gastrointestinal stromal tumor( GIST)DiagnosisSurgical managementTargeted therapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 298-301 )