Clinical application of serumβ-hydroxybutyric acid in diagnosis of diabetic ketoacidosis
YANG Xiu-lan
ZHU Xing-cheng
Abstract：Objective To explore the clinical value of serum β-hydroxybutyric acid in the diagnosis and treatment of diabetic ketoacidosis (DKA).Methods The levels of serum β-hydroxybutyric acid and blood glucose were examined in 105 diabetic patients without ketoacidosis , in 22 patients with DKA , and in 120 healthy controls . The relationships between β-hydroxybutyric acid and blood glucose in different groups were analyzed , and the clinical values were analyzed by ROC method .Results The sensitivity was 87.8%, specificity was 95.3%, and AUC was 0.947 in condition that the cut-off point was set at 1.97 mmol/L for identifying DKA from diabetic patients .Conclu-sion Serum β-hydroxybutyric acid has high accuracy for diagnosing DKA .
Keywords：Diabetic ketoacidosis(DKA)β-hydroxybutyric acidClinical application
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 247-249 )