Analysis of screening forα-thalassemia in 2 050 neonates in Laibin city
Abstract：Objective To screen for α-thalassemia in the neonates in Laibin city , and to provide the evi-dence for the clinical diagnosis , prevention and treatment of the disease .Methods Umbilical cord blood was collect-ed from 2 050 neonates in our hospital from May 2014 to April 2015 .The HbBart′s contents of the neonates were de-terminated by the agarose gel electrophoresis .The incidence of neonates with α-thalassemia was calculated .Results Two hundrend and seventy-two cases withα-thalassemia were checked out from 2 050 neonates .The positive rate was 13.27%, of which 137 cases(accounting for 50.37%) with static type,129 cases(accounting for 47.43%) with standard type, and 6 cases(accounting for 2.21%) with Hemoglobin H disease.Conclusion The agarose gel elec-trophoresis is an efficient method fror quickly screening out α-thalassemis in neonates .Laibin city is an area with a high incidence of α-thalassemia.Active prevention and controlling measures should improve the population quality in this area.
Keywords：Neonateα-thalassemiaUmbilical cord bloodHbBart′s contentAgarose gel electro-phoresis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 242-244 )