Effects of hemodialysis on inflammation and coagulation changes in patients with chronic kidney disease
Abstract：Objective To study the effects of hemodialysis on the inflammation and coagulation change in the CKD5 patients.Methods The CKD5 patients were chosen in the Affiliated Hospital of Luzhou Medical College from January 2013 to December 2014 and their coagulation and inflammatory markers were detected .Results Com-pared with those in the control group(n=35), CKD5 of blood coagulation and inflammation in the CKD5 group(n=57) were significantly increased gradually with the decline in glomerular filtration .Fg was significantly increased and CRP significantly decreased in the dialysis CKD5 group(n=40) than those in the non-dialysis group(n=17)(P<0.05 ) .Univariate correlation analysis showed that CRP was significantly positively correlated with Fg and D-D.Con-clusion CKD5 patients may have a hypercoagulable state and secondary fibrinolysis .Hemodialysis may aggravate these disorders .The hypercoagulable state in CKD 5 patients is closely related to inflammation and CRP may be the risk factor .
Keywords：Chronic kidney diseaseHemodialysisHypercoagulableInflammation
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 210-213 )