The comparison of the clinical effce t between high-flux hemodialysis and hemodiafiltration in the treatment of uremia
LEI Ming
ZHANG Hong
Abstract：Objective To investigate the efficacy of high-flux hemodialysis(HFHD) and hemodiafiltration ( HDF) in the treatment of uremia .Methods A retrospective analysis of 48 cases with uremia during February 2013 to August 2014 was conducted .The patients were randomly divided into two groups .The observation group ( n=24) was treated with HPD and the control group (n=24) was treated with HDF for 80 days.Creatinine, urea nitrogen and serum leptin were tested before and after the treatment , and the levels of serum leptin in both of the two groups were compared with that in 20 healthy people .Results There were no significant differences in the levels of creatinine , u-rea nitrogen and serum leptin between the control group and the observation group before the treatment .After the treatment, the levels of creatinine and urea nitrogen were significantly decreased in both of the observation group and the control group ( P<0.05 );but the level of serum leptin only decreased in the observation group ( P<0.05 ) .Con-clusion The level of serum leptin is significantly higher in the uremic patients than that in the healthy people .HF-HD can effectively reduce the levels of serum leptin , creatinine and urea nitrogen in patients with uremia .
Keywords：High-fluxHemodiafiltrationUremiaApplication effect
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 208-210 )