An experimental animal model of maxillary mucocilliary transport pathway
Abstract：Objective To explore the feasibility of establishing an experimental rabbit model of mucociliary transport system of maxillary sinus.Methods Twenty maxillary sinuses of 10 rabbits were included in this research. Local anaesthesia was performed.The size of bone window at the anterior wall of maxillary sinus was 1 cm ×0.8 cm. Transport pathway of methylthioninium chloride was observed by trasnasal endonasal endoscope for 1.5 hour.Results All experiments were smoothly finished under the local anaesthesia.The bone window size of 1 cm ×0.8 cm could be satisfactory for all experimental manipulations.Methylthioninium chloride was transported from inferior wall to anteri-or-inferior edge of the maxillary natural ostium directly, and then transported out of maxillary sinus at that site.Con-clusion White rabbits can be established to be experimental model of the research related to maxillary mucociliary transport system .
Keywords：RabbitMaxillary sinusMucocilliaAnimal model
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 116-118 )