A meta-analysis of long-term postoperative efficacy of complete mesocolic excision for colon cancer
Abstract：Objective To systemically assess the recurrence rate and survival rate of complete mesocolic ex-cision( CME) for colon cancer.Methods The controlled studies which were related to the treatment of traditional surgery and CME for colon cancer and published in the last eight years were retrieved from the electronic databases ( China National Knowledge Infrastructure, Wanfang Database, PubMed, Medline, Ovid, Embase, Cochrane ISI Web of Knowledge, Cochrane Database of Systematic Reviews).With strictly screening according to the standard, the quality of studies was evaluated.Selective trials′data were analyzed by the Review Manager 5.1 software.Results A total of five nonrandomized clinical trials were finally included, involving a total of 1 804 patients in the research (558 patients in CME group and 1 246 patients in control group) .The 5-year postoperative recurrence rate of CME was 9.99%on average.Meta-analysis showed that the postoperative disease-free survival and overall survival in CME group were significantly higher than those in the control group(P<0.05).Conclusion CME is safe and effective in accordance with the principles of oncology therapy and is expected to become a new standardized operation technique for colon cancer.
Keywords：Colon cancerComplete mesocolic excisionLong-term postoperative resultsMeta-analy-sis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 108-113 )