A multicenter investigation on the etiology in 889 adult patients with community-acquired pneumonia in Guangxi Zhuang Autonomous Region

doi:10.3969/j.issn.1674-3806.2016.02.04

Abstract：Objective To investigate the etiologic characteristics of the adult patients with community-ac-quired pneumonia( CAP) in the urban and rural areas of Guangxi Zhuang Autonomous Region, and facilitate the de-velopment of normalized diagnosis and treatment of CAP.Methods A prospective study was performed on 889 adult patients with CAP at 14 centers in Guangxi Zhuang Autonomous Region from January 2008 to December 2010.All the patients were divided into urban area group and rural area group according to the different geography distributions. The etiologic characteristics and the distribution of detected pathogens were compared between the two groups.Results 486 strains of pathogens were isolated from 422 patients with qualified serum samples and/or sputum cultures, inclu-ding Mycoplasma pneumoniae (138/486,28.40%), Haemophilus infulenzae (88/486,18.11%), Streptococcus pneumoniae(77/486, 15.84%), Klebsiella pneumoniae(53/486,10.91%) and Chlamydia pneumoniae(43/486, 8.94%) .Mycoplasma pneumonia infection and Pseudomonas aeruginosa infection were higher in the population of the rural area group than those in the urban area group(41.12%vs 19.72%and 5.58%vs 1.73%), while the pro-portions of Streptococcus pneumoniae infection and legionella pneumophila infection were lower in the rural area group than those in the urban area group(8.1%vs 21.11%and 3.05%vs 7.96%).In the CAP patients, bacteria(exclu-ding legionella pneumophila) were responsible for the infection in the urban group, and atypical pathogens were re-sponsible for the infection in the rural group.Conclusion Mycoplasma pneumoniae is the most common pathogen that leads to adult CAP in Guangxi Zhuang Autonomous Region.Haemophilus infulenzae and Streptococcus pneumon-iae are still the most popular pathogenic bacteria for CAP as well.Atypical pathogens are the most common pathogens in the urban areas but bacteria in the rural areas.