Effect of potassium sodium hydrogen citrate therapy on stone recurrences and residual stones after percuta-neous nephrolithotomy for renal calculi
Abstract：Objective To evaluate the efficacy of potassium sodium hydrogen citrate on residual stone re-moval and prevention of stone recurrence after percutaneous nephrolithotomy(PCNL) for renal calculi.Methods One hundred and fifty-four patients with residual stones or without residual stones after PCNL were enrolled in this study.Patients without residual stones(n=84) or with residual stones(n=70) were randomly divided into the treat-ment group and the control group respectively.The treatment group was given orally potassium sodium hydrogen cit-rate granules 10 g per day, and the control group was not treated with any medication.The stone recurrence was com-pared between the two groups after a follow-up of 12 months.Results For patients without residual stones, the stone recurrence rate in the treatment group was significantly lower than that in the control group(8.33%vs 38.46%, P<0.05).For patients with residual stones group, the stone growth rate in the treatment group was also significantly lower than that in the control group(10.71%vs 59.37%, P<0.05).Conclusion Potassium sodium hydrogen cit-rate therapy can not only reduce the stone recurrence, but also inhibit the residual stone growth after PCNL.
Keywords：Percutaneous nephrolithotomyPotassium sodium hydrogen citrateRenal calculi
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1027-1030 )