Detection of Mitochondrial tRNA Leu(UUR) Mutations at Position A3243G in Newborns of diabetic preg-nant women in Guangxi
Abstract：Objective To investigate the frequencies of the mitochondrial tRNA Leu( UUR) mutations at po-sition 3243A/G in newborns of diabetic pregnant women in Guangxi.Methods The point mutations of tRNA Leu ( UUR)3243A/G in 50 newborns of diabetic pregnant women and 50 newborns healthy controls were detected by DNA sequencing.Results No one carrying the mitochondrial tRNA Leu(UUR)3243A/G mutation was found in the two groups.Conclusion The mitochondrial tRNA Leu(UUR)3243A/G mutation may not yet be an important genetic predisposing factor of prenatal screening for gestational diabetes mellitus in Guangxi.
Keywords：Gestational diabetes mellitusMitochondrial tRNA Leu(UUR)3243A→GMutationsNewbornsPrenatal screening
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1025-1027 )