Clinical evaluation of the recurrence risk of primary liver cancer after resection with the ratio of alpha feto-protein and standard remnant liver volume
Abstract：Objective To evaluate the clinical value of the ratio of the alpha fetoprotein( AFP) and standard remnant liver volume in the recurrence risk of primary liver cancer after resection.Methods Sixty-eight patients′clinical data were retrospectively analyzed, who were given the primary liver cancer resection in our hospital from May 2009 to September 2014, with a follow-up of 1 year.They were divided into two groups according to whether the dis-ease reoccurred or not.The recurrence group contained 32 patients, and the non-recurrence group contained 36 pa-tients.The mean AFP and standard postoperative residual liver volume were compared between the two groups to eval-uate the clinical value of the ratio of the alpha fetoprotein( AFP) and standard remnant liver volume in the recurrence risk of primary liver cancer after the resection.Results The postoperative AFP was ( 110.25 ±89.44 ) ng/ml and (70.71 ±54.32)ng/ml respectively in the recurrence group and the non-recurrence group;The standard remnant liv-er volume was (371.59 ±27.35) ml/m2 and (462.56 ±61.96) ml/m2 respectively in the recurrence group and the non-recurrence group.The ratio of AFP to standard remnant liver volume of the recurrence group was ( 0.29 ± 0.22), which was significantly higher than that of the non-recurrence group(0.16 ±0.16)(P<0.01).Conclusion There is certain clinical value of the ratio of AFP to standard remnant liver volume in the recurrence risk of primary liver cancer after resection.When it exceeds 0.2, the recurrence risk of primary carcinoma of the liver after resection will be higher in 1 year.
Keywords：Alpha fetoprotein( AFP)Hepatocellular carcinomaStandard remnant liver volumeRe-currence
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 919-921 )