The effects of Huzhangjiangzhi granules on hyperlipidemia in rats
Abstract：Objective To study the therapeutic effects of HuzhangJiangzhi Granules on hyperlipidemia in di-et-induced rats.Methods The hyperlipidemia rat model was induced by administrating with high fat emulsion and different doses of HuzhangJiangzhi Granules were given orally to rats.The effects of the drug on the levels of lipids, AST, ALT, creatinine, urea nitrogen in serum, the levels of TC, TG in liver, the liver index and morphologic chan-ges of liver were observed.Results HuzhangJiangzhi Granules in different doses reduced significantly the levels of liver index, liver TC and TG, serum TC, LDL-C and HDL-C, serum AST and ALT( P<0.05 or P<0.01) , but had no effects on serum TG levels, serum creatinine and urea nitrogen.The results of liver histopathology indicated that HuzhangJiangzhi Granules reduced significantly liver steatosis.Conclusion HuzhangJiangzhi Granules can regulate hyperlipidemia in rats.
Keywords：Huzhangjiangzhi granulesSerum lipidLiver lipidHyperlipidemia
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 901-906 )