The effect of lung protective ventilation strategies on acute respiratory distress syndrome
ZHONG Hua-qiang
HUANG Ke-zan
Abstract：Objective To evaluate the clinical effect of lung protective ventilation strategies on acute respira -tory distress syndrome ( ARDS) .Methods 62 patients with acute respiratory distress syndrome were randomly divid-ed into the control group(n=30) and the observation group(n=32).The control group was treated with convention-al ventilation strategy , and the observation group was treated with lung protective ventilation strategies .PaO2 , PaCO2 , PaCO2/FiO2 and ventilation time, hospitalization days and the rate of ventilator associated lung injury (VALI) were compared between the two groups .Results PaO2 , PaCO2 and PaO2/FiO2 at 8 h, 24 h and 48 h after ventilation in the observation were signigicantly higher than those in the control group ( P<0.05 ) .The ventilation time , hospitali-zation days and the rate of VALI in the observation group were signigicantly shorter or lower than those in the control group(P<0.05).Conclusion Using lung protective ventilation strategies for acute respiratory distress syndrome can signigicantly shorten the ventilation time , hospitalization days and reduce the incidence of VALI .It has important clinical significance for ARDS .
Keywords：Lung protective ventilation strategiesAcute respiratory distress syndrome ( ARDS)Clinical effect
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 845-848 )