Effects of smearing hormonal drugs on artificial vaginal epithelium after laparoscopicperitoneal vaginoplasty
Abstract：Objective To investigate the postoperative effects on the micro-ecology of artificial vagina after smearing hormonal drugs on the patients undergoing the laparoscopic peritoneal vaginoplasty .Methods 80 patients with congenital absence of the vagina were selected and divided into the observation group and the control group .All patients underwent laparoscopic peritoneal vaginoplasty .The patients in the observation group were treated with estra-diol benzoate based on the above treatment .The secretions on the artificial vaginal wall were extracted and the micro-ecology of vagina was detected when the filling yarn in the vagina was taken out on the first day , the first week,the second week, the third week and the three and six months (labeled T0~T5) after discharge.Other 40 healthy exam-ined people were selected as the control group who were performed the same detection on the first examination day and at the end of the first week , the second week, the third week , the third month and the sixth month .Results The ar-tificial vagina pH in the observation group during the period of T 0~T1was close to that in the operation control group but higher than that in the control group ( P<0.05 ) .The artificial vagina pH in the observation group during the peri-od of T2~T4 was significantly lower than that in the operation control group ( P<0.05 ) , but was significantly higher than that in the control group ( P<0.05 ) .The artificial vagina pH in the observation group during the period of T 5 was close to that in the control group .The normal rate of micro-ecology of the artificial vagina in the observation group during the period of T0~T3 was close to that in the operation control group but significantly lower than that in the control group ( P<0.05 ) .The indexes above in the observation group during the period of T 4~T5 were basically nor-mal.The vaginal dominant bacteria in the control group during the period of T 0~T3 and in the observation group during the period of T 0~T1 were gram positive small coli .The vaginal dominant bacteria in the two groups during other time slots and in the control group were gram positive bacteria .Conclusio n Application of hormonal drugs can improve the micro-ecology of artificial vagina after the peritoneal vaginoplasty .
Keywords：LaparoscopePeritonealVaginoplastyEstradiol benzoateMicroecology
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 723-725 )