Postoperative patient controlled intravenous analgesia with tramadol combined with different doses of sufen-tanil after gastrointestinal surgery
HUANG Jun-shu
Abstract：Objective To evaluate the efficacy of postoperative patient controlled intravenous analgesia ( PCIA) with tramadol combined with different doses of sufentanil after gastrointestinal surgery .Methods According to admission date , 60 patients undergoing gastrointestinal surgery were randomly divided into three groups with 20 pa-tients in each group .Group A received tramadol 300 mg and sufentanil 50 μg.Group B received sufentanil 100 μg and tramadol 300 mg.Group C received tramadol 300 mg and sufentanil 150μg.Analgesia drugs in each group were added droperidol 2.5 mg and diluted with normal saline to 100 ml.Patient controlled analgesia(PCA) pumps were connected before the end of operations .The mode of analgesia: the load dose was 2 ml, the maintenance dose was 1.2 ml/h, PCA was 2 ml and the locking time was 20 min.The whole observing course was 24 h.Visual analogue scale( VAS) , Ramsay sedation score and side effects were recorded at 2~4 h,8~10 h,12~20 h and 22~24 h re-spectively after the operation .Results The VAS scores in group B and group C at each stage after the operation were lower than that in group A ( P=0.000 ) .The VAS score in group C at each stage was lower than that in group B after the operation ( P=0.000 ) .There was no significant difference in Ramsay sedation score at each stage after the opera -tion among the three groups .Conclusion Tramadol 300 mg combined with sufentanil 150 μg is effective and safe for postoperative PCIA in patients undergoing gastrointestinal surgery .
Keywords：Gastrointestinal diseasesSurgeryTramadolSufentanilPatient controlled intravenous analgesia(PCIA)
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 647-649,650 )