The risk factors of pulmonary fungal infections in elderly patients with chronic obstructive pulmonray disease
Abstract：Objective To explore the risk factors of pulmonary fungal infections in elderly patients with chronic obstructive pulmonary disease ( COPD) .Methods 85 COPD patients complicated with pulmonary fungal in-fections and other 60 COPD patients without pulmonary fungal infections were selected .The clinical data of the two groups were collected and comparatively analyzed .Meanwhile , the distribution of funguses was observed by fungal cultures and identification .Results There were significantly differences in the time of using antibacterial drugs , the levels of serum albumin , the numbers which used glucocorticoid more than 2 weeks , complication with diabetes , re-spiratory failure , and using mechanical ventilation between the observation group and the control group ( P<0.01 ) . Multifactor regression analysis indicated that long-term use of antibiotics , glucocorticoid , hypoalbuminemia , diabetes and respiratory failure , mechanical ventilation were the risk factors of pulmonary fungal infections in elderly patients with COPD(P<0.05).In fungal infections, the main strain is Candida, among which Candida albicans accounted for the highest detection rate .Conclusion Antibiotics and glucocorticoid should be rationally used for the treatment of COPD and avoiding excessive use of invasive mechanical ventilation and paying more attention to the treatment of complications are also helpful for pulmonary fungal infections .
Keywords：Chronic obstructive pulmonary disease ( COPD)Pulmonary fungal infectionClinical diag-nosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 630-633 )