The correlation between semen quality, sperm DNA integrity rate and working hours in infertility male driv-ers

doi:10.3969/j.issn.1674-3806.2015.06.08

Abstract：Objective To study the correlation between semen quality, sperm DNA integrity rate( DNA frag-mentation index, DFI ) and working hours in infertility male drivers.Methods 150 infertility male patients(inclu-ding 110 occupational drivers, 40 patients who never drove ) , were divided into 3 groups according to the driving hours every day:group A with driving 1~5 hours every day( n=50);Group B with driving >5 hours every day( n=60);Group C without driving every day(n=40).The semen quality and sperm DNA integrity rate were analyzed in the patients.Results (1) The quantity, vitality, concentration of sperms and PR in group C were higher than those in group A, B respectively [ ( 3.10 ±1.32 ) ml vs ( 2.16 ±0.88 ) ml, ( 1.27 ±0.72 ) ml; ( 39.01 ±9.01 )% vs (27.38 ±6.00)%, (21.34 ±7.95)%;(25.80 ±17.92)106/ml vs (12.60 ±4.59)106/ml, (7.66 ±2.92)106/ml;(5.35 ±1.89)%vs (3.06 ±0.68)%, (2.10 ±0.82)%], P=0.000.(2)The motility and normal morphology of the sperms and PR in group A were higher than those in group B[(2.16 ±0.88)ml vs (1.27 ±0.72)ml;(27.38 ± 6.00)%vs (21.34 ±7.95)%; (3.06 ±0.68)% vs (2.10 ±0.82)%], P=0.000.There was no significant difference in the sperm concentration between the two groups[(12.60 ±4.59)106/ml vs (7.66 ±2.92)106/ml]. (3)DFI(%) of group B was higher than that of group A and group C[(21.54 ±12.28)%vs (13.00 ±8.29)%, (10.15 ±6.75)%], P=0.000;DFI(%) was not significantly different between group A and group C[(13.00 ± 8.29)%vs (10.15 ±6.75)%], P=0.172.Conclusion Male drivers have poorer quality or quantity in sperm concentration, vitality, normal form and DNA integrity than the male controls who never drive and the longer time the male drivers drive, the poorer quality of the sperms they will have.