Analysis of linezolid in the treatment of 27 patients with severe sepsis in intensive care unit
XIANG Shu-lin
XIONG Bin
Abstract：Objective To analyze the clinical efficacy and safety of linezolid in the treatment of severe sepsis in intensive care unit.Methods Twenty-seven patients with severe sepsis were treated with linezolid 0.6 gram twice per day and the blood routine examination, liver and renal function were tested before and 72 h after the medication to analyze the efficiency and safety of the treatment.Results The clinical efficacy rate was 70.37%, and there were no significant differences in the blood routine examination, liver and renal function before and after 72 hours′treatment of linezolid(P>0.05).Conclusion Linezolid has conspicuous effectiveness and safety in the treatment of severe sep-sis within 72 h in intensive care unit.
Keywords：LinezolidSevere sepsisDrug safety
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 513-515 )