Meta-analysis of laparoscopic and open repair of perforated peptic ulcer
Abstract：Objective To study the safety and efficacy of laparoscopy and open repair for patients with perfo-rated peptic ulcer.Methods Articles published in Chinese and English were searched in the Cochrane Library and on the databases of PubMed, EMBASE, CNKI, Wanfang from January 1990 to September 2014, to meet the search-ing requirements.Meta-analysis was used to analyze the collected data.Results The data of 6 randomized clinical trials of acceptable quality were collected from the databases,including a total of 682 patients, 362 cases of laparo-scopic group and 320 cases of open group.The results showed that there were no statistically significant differences between laparoscopic and open surgery in the operative time(P=0.37), intra-abdominal abscess(P=0.57) and mor-tality(P=0.34).Conclusion Laparoscopic surgery is safe and feasible.However, more randomized controlled tri-als with a greater number of patients need to be performed to confirm such an assumption.
Keywords：Laparoscopic repairPerforated peptic ulcerMeta-analysis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 422-427 )