Research on nosocomial infection and drug resistance of staphylococcus aureus
JIANG Li-li
Abstract：Objective To study the nosocomial infection features and drug resistance of Staphylococcus au -reus and provide a clinical evidence of antibiotics selection .Methods The isolated bacteria were identified and anti-biotic sensitivity was detected using K-B disk diffusion method according to standard CLSI /NCCLS requirement in 196 strains of Staphylococcus aureus collected in Dachang hospital of Nandan county from January 2012 to June 2014 . Results In 196 strains of Staphylococcus aureus , methicillin-resistant Staphylococcus aureus ( MRSA) accounted for 46.4%(91/196), the methicillin sensitive staphylococcus aureus (MSSA) accounted for 53.6%(105/196).Most of MRSA infections were found in elderly patients in respiratory department .The sensitivity rate of both MRSA and MSSA to vancomycin, linezolid and teicoplanin was 100.0%.The resistance rate of MRSA to ampicillin, oxacillin, penicillin, cefazolin, cefoxitin was 100.0%.The resistant rate of MSSA to penicillin , ampicillin, erythromycin was decreased successively .The drug resistant rate of MRSA to antibiotics was higher than that of MSSA ( P<0.05 ) . Conclusion The drug resistance of MSSA and MRSA to antibiotics was different .The monitoring drug resistance of MRSA should be further strengthened clinically in order to control the drug resistant strains and reasonably use antimi -crobial drugs .
Keywords：Staphylococcus aureusMethicillin-resistant staphylococcus aureus ( MRSA)Drug sensitiv-ity testDrug resistance
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 352-354 )