Ultrasonic evaluation on the relationship between carotid atherosclerotic plaques and blood glucose fluctua-tion in patients with type 2 diabetes
TAN Jie-lin
Abstract:Objective To study the relationship between the carotid atherosclerotic plaque and blood glucose fluctuations in patients with type 2 diabetes(T2DM).Methods According to the carotid artery color doppler ultra-sonography, 198 patients with T2DM were divided into no carotid sclerosis group (group A, n=53), the stable carot-id atherosclerosis plaque group(group B, n=68), and unstable carotid atherosclerosis plaque group (group C, n=77) .Dynamic glucose monitoring system ( CGMS) was used to continuously monitor 72 h blood sugar , calculate the mean blood glucose(MBG), within-day mean amplitude of glycemic excursion (MAGE), and recorded the age, blood pressure, glycated hemoglobin(HbA1c), serum total cholesterol(TC), triglycerides(TG), low-density lipoprotein cholesterol(LDL-C), high density lipoprotein cholesterol(HDL-C), and gender.Results Among the three groups, there were statistically significant differences in systolic pressure , diastolic blood pressure , FPG, TC, HDL-C, LDL-C and HbA1c, and MBG, MAGE gradually increased with the degree of carotid artery atherosclerosis (all P<0.05). Conclusion In patients with T2DM, the blood sugar fluctuation increases the risk of carotid atherosclerotic plaques , therefore the dynamic blood sugar monitoring should be paid attention to .
Keywords:Type 2 diabetes(T2DM)Blood glucose fluctuationDynamic blood sugar monitoringCarotid intima -media thicknessAtherosclerotic plaques
Publication Date:2015-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:4( 324-327 )
