Practice in special prescription evaluation of bisphosphonates agent

CHEN Ying; XI Jia-xi; YE Dong-mei

doi:10.3969/j.issn.1674-3806.2015.02.09

Abstract：Objective To investigate the utilization of bisphosphonates agents in outpatients and inpatients of the People′s Hospital of Guangxi Zhuang Autonomous Region, and explore work model and method of special pre-scription evaluation.Methods All the electronical prescriptions of bisphosphonates agents of the outpatients and in-patients from April 2013 to March 2014 were analyzed retrospectively.The prescription rate and structure ratio of bi-sphosphonates agents were calculated.By setting the bisphosphonates agents prescription evaluating standard,the med-ication rationality of each sample prescription was evaluated and inappropriate prescriptions were classified and ana-lyzed.Results 3 080 bisphosphonates agents prescriptions were collected from outpatients from April 2013 to March 2014 in which zoledronic acid ( the prescription rate of 51.75%) and alendronic acid ( the prescription rate of 43.54%) were used mostly.2 958 bisphosphonates agents prescriptions were collected from inpatients from April 2013 to March 2014 in which zoledronic acid( the prescription rate of 63.72%) and pamidronate disodium( the pre-scription rate of 25.56%) were used mostly.689 inappropriate prescriptions accounted for 11.67% of the bisphos-phonates agent prescriptions.The inappropriate prescriptions were related to inappropriate indication(27.00%),inap-propriate usage and dosage ( 44.99%) , drug interaction ( 19.59%) and other inappropriate prescriptions ( 8.42%) . Conclusion The practice in special prescription evaluation is helpful to discover some typical inappropriate medica-tions in the prescriptions, which is supposed to provide scientific evidence for intervention and continuous improve-ment of rational medication.