The value of procalcitonin in the discrimination between sepsis due to different bacterial
WANG Yan-shuang
HE Ya-jun
Abstract：Objective To explore the value of procalcitonin( PCT) in the discrimination between sepsis due to Gram-negative( GN) bacteria and duo to Gram-positive( GP) bacteria.Methods One hundred and one sepsis pa-tients with positive blood culture between January 2013 to May 2014 were collected in Guangzhou Red Cross Hospital. Among them, 56 patients were infected with GN bacteria and the other 45 patients were infected with GP bacteria. Serum PCT, hs-CRP and WBC count were detected.Drawing PCT ROC curve aimed to analyze the best cut-off score and the sensitivity and the specificity were made.Results Serum PCT levels were obviously higher in patients with GN bacteria(M=18 ng/ml)than those in patients with GP bacteria(M=3.6 ng/ml).According to the ROC curve, the best cut off was 3.22 ng/ml with the sensitivity 86% and the specificity 72% and the area under the curve (AUC) was 0.864.Conclusion PCT may be a sensitive index for discrimination between sepsis due to Gram-nega-tive bateria and due to Gram-positive bacteria.
Keywords：Procalcitoninhs-CRPWBC countSepsis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 24-26 )