Curative effect observation of cardiotonic and diuretic mixture in the treatment of refractory heart failure:report of 36 cases
LI Bin
Abstract：Objective To investigate the curative effect of cardiotonic and diuretic mixture in the treatment of refractory heart failure .Methods Thirty-six refractory heart failure patients who had not response to conventional cardiac, diuretic, vasodilator (digitalis, phosphodiesterase inhibitors , ACEI, furosemide and so on) were treated by cardiotonic and diuretic mixture composed of small dose of dopamine , dobutamine , nitroglycerin , aminophylline , to-rasemide injection etc .Results The marked effect was found in 25 cases ( NYHA decreased from grade Ⅳ toⅠ~Ⅱ), effectively in 7 cases(NYHA decreased from grade ⅣtoⅡ~Ⅲ), no effect in 4 cases(heart failure symptoms had no obvious change ) .There were statistically significant differences in heart rate , hemodynamic left ventricular e-jection fraction(LVEF), left ventricular end-systolic diameter(LVESD) and other indicators before and affer treat-ment(P<0.01).Conclusion The cardiofonic diuretic mixture composed of dopamine , dobutamine, nitroglycerin, aminophylline, torasemide injection etc has marked effect in treating refractory heart failure patients who had not re -sponse to conventional cardiotonic and diuretic therapy .
Keywords：Cardiotonic and diuretic mixtureRefractory heart failureCurative effect observation
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1050-1052 )