Diagnosis and treatment of 4 patients with granulocytic sarcoma and the literature review
Abstract：Objective To explore the diagnosis, clinical pathology, immunohistochemistry, cytogenetics and treatment of granulocytic sarcoma(GS). Methods The clinical data of 4 cases of GS was analyzed, and the related-literatures were reviewed. Results Two cases were non-leukemic GS, currently being in continuous complete remis-sion after appropriate treatment. The other 2 cases were leukemic GS:one case originated from acute myeloid leuke-mia, and the other one originated from chronic myeloid leukemia, the results of the two patients for treatment were poor, the survival time of the two cases was 8 months and 4 months respectively. Conclusion The diagnosis and dif-ferential diagnosis of GS mainly depends on patho-morphology and immunohistochemistry. The prognosis of GS is poor.The early diagnosis, timely implementation of the individualized treatment and early high-intensity chemothera-py can delay the recurrence and improve long-term survival rate;hematopoietic stem cell transplantation can signifi-cantly prolong survival time.
Keywords：Granulocytic sarcomaCytogeneticsDiagnosisTreatment
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1024-1028 )