Study on the influence of different anesthesia methods on elderly patients′postoperative cognitive dysfunction
MA Ya-bing
Abstract：Objective To investigate the influence of different anesthesia methods on elderly patients ′post-operative cognitive dysfunction by mini-mental state examimation ( MMSE) to test neuropsychology .Methods From January 2010 to January 2011 180 elderly patients with ASAⅠ~Ⅱ,who underwent selective non-cardiac surgery, were randomized into two groups , with 90 cases in each group .One group was treated with epidural anesthesia ( epi-dural group ) and the other with general anesthesia ( general group ) .The general situation was compared between two groups.The scores of MMSE before anesthesia , at 3 hours, 9 hours,3 days,5 days after operation and rate of postop-erative cognitive dysfunction (POCD) were recorded.Results There was no significant difference in general situation between two groups ( P>0.05 ) .The score of MMSE after anesthesia in each group were all reduced;The score of MMSE in two groups were statisticant differences ( P<0.05 );The score of MMSE in different times were statisticant differences ( P<0.05 ) .There was significant difference in rate of POCD between epidural group and general group at 3 hours and 9 hours after operation ( P<0.05 ) .There was no significant difference in rate of POCD between epidural group and general group at 3 days and 5 days after operation ( P>0.05 ) .Conclusion Both of epidural anesthesia and general anesthesia associated with postoperative cognitive dysfunction ,but general anesthesia technique has a pow-erful influence on cognitive function than epidural anesthesia .
Keywords：AnesthesiaThe elderlyPostoperative cognitive dysfunction
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1015-1017 )