Application value of MRI in the diagnosis of liver hemochromatosis
YU Shui-lian
MA Long-bai
LIU Ying
Abstract：Objective To analyze the manifestations of MR T2 WI and dual echo T1 WI in liver hemochroma-tosis, and evaluate the value of MRI in the diagnosis of live hemochromatosis.Methods The MRI of 27 confirmed patients with liver hemochromatosis were retrospectively analyzed, the liver signal intensity on T2 WI and dual echo T1 WI were observed.Results All 27 patients′T2 WI showed liver signal intensity reduced in a certain extent, closed to or lower than the sacrospinal muscle signal intensity on the same slice.Dual-echo T1 WI also showed the liver sig-nal intensity reduced in both in-phase and opposed-phase images, however on the in-phase images the signal intensi-ty′s loss was more obvious than the opposed-phase images.The liver signal intensity was higher on the opposed-phase images than the in-phase images.Nine patients showed signal intensity reduced in spleen, and also display higher sig-nal intensity on opposed-phase images.Conclusion T2 WI combined with dual echo T1 WI have high degree of sensi-tivity and specificity for the diagnosis of hemochromatosis.MRI has very important clinical value for early diagnosis and treatment monitoring of hemochromatosis.
Keywords：LiverHemochromatosisDual-echoMagnetic resonance imaging
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 921-924 )