Effects of synchronous chemoradiation therapy versus radiation therapy alone in the treatment of local medi-um-term and advanced cervical cancer
GAN Zu-huan
GAN Lang-ge
Abstract：Objective To explore the synchronous chemoradiotherapy of clinical curative effect and adverse reaction of synchronous chemoradiation therapy in the treatment local medium-term and advanced cervical cancer . Methods According to random number table method ,one hundred and twenty patients withⅡb-Ⅳa cervical cancer receiving initial treatment were divide into synchronous chemotherapy group (60 cases) and simple radiotherapy group ( 60 cases ) .Results Between two groups there were statistically significant difference in short-term therapeutic effect,5-years′survival rate,local recurrence rate and distant metastasis rate in 5-year(P<0.05);and there were sta-tistically significant difference in gastrointestinal reaction,bone marrow suppression(P<0.05);no significant differ-ence were observed in the radiation proctitis and radioactive ,cystitis(P>0.05).Conclusion Synchronous chemora-diotherapy can improve short-term therapeutic effect of local medium-term advanced cervical cancer , improve the 5-year survival rate, reduce local recurrence rate and distant metastasis rate in 5-years,but significantly increase the gastrointestinal reaction and bone marrow suppression .
Keywords：Cervical cancerSynchronous chemoradiationCurative effect
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 834-837 )