Clinical experience on diagnosis and treatment of 26 patients with hyperthyroidism complicated by periodic paralysis
JIANG Jia-jun
Abstract：Objective To investigate the clinical featurs of hyperthyroidism patients with periodic paralysis in order to dearease the rate of missed diagnosis and misdiagnosis .Methods A retrospective analysis of the clinical data was performed of 26 patients with hyperthyroidism complicated by periodic paralysis .Results Within 1to 18 h after potassium treatment , the patients′symptoms and signs quickly relieved , and after antithyroid drug treatment thy-roid function returned to normal in 22 patients.Two patients experienced 2 times of recurrent attacks and their thyroid function returned to normal after adjusting antithyroid drug .Due to adverse reaction of oral drugs ,2 patients were trea-ted with 131 I treatment instead of oral drugs and their thyroid function returned to normal after 131 I treatment.Within 6 to 12 months of follow-up,no recurrence of periodic paralysis appeared in 26 patients.Conclusion For patients with hyperthyroidism complicated by periodic paralysis , potassium supplementation can rapidly improve their symptoms;active and effective antithyroid drugs treatment is key to preventing recurrence ;at the same time , it is necessary to a-void the predisposing factors such as overeat ingestion , infection, excessive exertion , and intravenous infusion of hy-pertonic glucose and so on ,in order to prevent recurrence .
Keywords：HyperthyroidismPeriodic paralysisExperience
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 732-734 )