Impact of blastocyst biopsy on the embryos development potential and survival rate after vitrification
Abstract：Objective To investigate the impact of blastocyst biopsy on the development potential and sur-vival rate after vitrification of different quality blastocysts .Methods The surplus embryos in IVF-ET cycles were al-located to good or poor quality blastocysts group by the embryo grade in day 5/6, and the same quality blastocysts were allocated to biopsy and control group .For the blastocysts from biopsy group trophectoderm removal was per-formed and then the survival blastocysts were vitrificated , but for control group vitrification was performed without bi-opsy.The survival rate after blastocyst biopsy and warming were compared between different groups .Results For the poor quality blastocysts group the survival rate after blastocyst biopsy was lower than the good quality blastocysts group, but the difference was not significant ( P=0.183 ) , and the survival rate after warming was significantly lower than the good quality blastocysts group ( P=0.001 ) .But the survival rate after warming was similar between the biop-sy group and control group(P=0.597,P=0.823).Conclusion Blastocyst biopsy did not impair the development potential and survival efficient after vitrification .
Keywords：Preimplantation genetic diagnosisBlastocystBiopsyVitrification
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 596-599 )