Randomized controlled trial comparing three methods in weaning patients with AECOPD
Abstract：Objective To compare the difference among smart-care weaning , protocol-directed weaning and experience-based weaning in weaning patients with acute exacerbation of chronic obstructive pulmonary disease ( AE-COPD) .Methods Ninety-six patients with AECOPD receiving invasive mechanical ventilation , were selected and randomly divided into three groups .Results Smart-care weaning method and protocol-directed weaning method were significantly shorter than experience-based weaning method in the duration of mechanical ventilation ( MV ) ( P <0.01), the length of stay in the ICU(P<0.01).And the incidence rate of ventilator associated pneumonia (VAP) were 18.8%, 25.0%, 46.9%,respectively ,showing significant difference among three groups ( P<0.05 ) .Howev-er, there was no significant difference in ICU mortality , extubation successful rate and rates of reintubation within 48 hours(all P>0.05).Conclusion The smart-care weaning method and protocol-directed weaning method can short-en the duration of MV and the length of stay in the ICU , and reduce the incidence rate of VAP .
Keywords：Mechanical ventilationWeaningSmart-care weaningProtocol-directed weaningA-cute exacerbation of chronic obstructive pulmonary disease ( AECOPD)
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 404-407 )