Animal experimental study of dermal toxicty of Zhuangyi Tonglu Medicinal Liquor
Abstract：Objective To observe toxic reactions in the experimental rabbits after skin touching the Zhuangyi Tonglu Medicinal Liquor.Methods The experimental rabbits weighing (2.5 ±0.25)kg were used as testing animal, then randomly divided into groups and molded according to the half genders standard .Each experimental groups were smeared Zhuangyi Tonglu Medicinal Liquor onto the wound or the normal skin while the control group was smeared rice wine.Dermal reactions of different groups were observed .Results The normal and wounded skin of rabbits in different groups showed no acute toxicity and long term toxicity , and Zhuangyi Tonglu Medicinal Liquor did not cause dermal irritation of rabbits .The experimental groups showed no significant difference compared with the control group ( P>0.05) .Conclusion Treating arthralgia syndrome with Zhuangyi Tonglu Medicinal Liquor by the means of topi -cal skin smearing has reasonable security .
Keywords：RabbitsZhuangyi Tonglu Medicinal LiquorAcute toxicityLong term toxicityDermal irritation
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 397-401 )