Comparative analysis of the manifestations of MSCT and MRI and the pathological features of maligant pe-ripheral nerve sheath tumor:report of 17 cases
SUN Pei-yi
WANG Zheng
WEI Xiao-mei
Abstract：Objective To analyze the maligant peripheral nerve sheath tumors ( MPNST)′MSCT, MRI ima-ging and pathological features in order to improve its diagnostic accuracy .Methods The retrospective analysis of 17 cases of MPNST confirmed by operation and pathology were performed .Results There were 4 cases in the upper limb, 4 cases in the lower extremity , 3 cases in the neck and back , 3 cases in the sacroiliac joint area , 2 cases in in-traspinal area , 1 case in the esophagus .The huge tumor usually showed necrosis and haemorrhage but rare calcifica-tion.MSCT scan was mainly manifested as mixed hypodensity and isodensity irregular huge mass shadow , T1 WI mainly showed iso-/slight hypo-intensities, T2 WI and STIR mostly showed mixed hyper-/hypo-intensities.Contrast enhanced scan showed obvious ringlike enhancement about the edge of tumor and displayed nodous or patchy funicular heterogeneous enhancement of solid component within tumor .Pathology: the tumor had pseudocapsule and mainly showed the ball or spindle form .It showed more haemorrhage necrosis than cystic change and infrequent calcification . The tumor cell showed the varied forms and mainly was the spindle cell .The sensitive makers of the tumor were NSE , S-100, CD56, Vimentin, which showed more positive .Conclusion MPNST often occur in the thick neural stem′s walk line area ,there is a strong correlation between the manifestations of MSCT and MRI and the pathological fea -tures, The combination of the theirs is helpful in improving the level of diagnosis and differential diagnosis .
Keywords：Nerve sheath tumorsX-ray computed tomographyMagnetic resonance imagingPathology
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 310-313 )