Clinical analysis of pneumonia infected with escherichia coli in 177 infants

doi:10.3969/j.issn.1674-3806.2014.02.05

Abstract：Objective To analyze the clinical characteristics and antimicrobial susceptibility of pneumonia infected with Escherichia coli in infants for clinical pneumonia treatment .Methods Retrospective analysis was per-formed for 177 cases of pneumonia infected with Escherichia coli in hospitalized infants with clinical manifestations , X-ray findings , bacterial drug resistance and treatment outcome .Results The main symptoms of clinical manifesta-tions in infants of pneumonia infected with Escherichia coli were cough , sputum, fever, and likely to prone to breath-ing difficulties .X-ray mainly showed patchy or interstitial exudation .The drug sensitivity test showed that Escherichia coli were sensitive to tienam, mei-ping, ceftazidime, amikacin,levofloxacin, piperacillin/tazobacta and cefopera-zone/sulbactam.While they were resistant to most β-lactam antibiotics.There were 33 cases of pneumonia of Esche-richia coli with producing extended-spectrum β-lactamase(ESBLs) bacteria with 18.6% positive rate.The negative conversion sputum culture of Escherichia coli in pneumonia infants was relatively slow .Treatment for pneumonia in-fected with Escherichia coli in infants was mainly empirical therapy combined with drug susceptibility test results ac -cording to sputum culture of Escherichia coli , while the prognosis of pneumonia infected with Escherichia coli was still good although prolonged course .Conclusion Escherichia coli pneumonia in infants was a common pediatric disea-ses, which clinical diagnosis relatively easy .However, there be likely needed to pay attention to higher antimicrobial resistance to Escherichia coli .