The application of paclitaxel liposome combined with cisplatin regimens as induction chemotherapy in the treatment of advanced cervical cancer
GUO Yi
ZHU Jin-xian
Abstract：Objective To evaluate the efficacy and toxicity of paclitaxel liposome combined with cisplatin as induction chemotherapy in the treatment of cervical cancer .Methods Seventy-three patients who received chemo-therapy of paclitaxel liposome combined with cisplatin (TP program) and 5-fluorouracil(FP regimens) were retrospec-tively analyzed .There were 41 patients in TP group and 32 patients in FP group .All patients received induction chemo-therapy combined with the afterloading radiotherapy 15~20 Gy for two courses of treatment .Results The efficiency of TP group and FP group were 75.6%and 46.9%respectively , the efficient of TP group was higer than FP group ( P<0.05 ) ,there was no statistically significant difference in the toxic side effects between two groups ( P all >0.05 ) . Conclusion Chemotherapy of paclitaxel liposome combined with cisplatin is a very effective induction chemotherapy which can control the progression of tumor and treat the tumor before surgery .
Keywords：Cervical cancerInduction chemotherapyCisplatinPaclitaxel
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1187-1189 )