Clinical effect of frozen jiaweisanhuangtang in the prevention of radiation-induced neck skin damage in pa-tients with nasopharyngeal carcinoma
Abstract：Objective To observe the clinical effect of frozen jiaweisanhuangtang in the prevention of acute radiation-induced neck skin damage in patients with nasopharyngeal carcinoma .Methods Thirty-one patients with nasopharyngeal carcinoma undergoing radiotherapy were enrolled in the study , frozen jiaweisanhuangtang were applied to right-neck as treatment group , and left-neck were as a blank control group .Results The time of occurrence of skin injury at right-neck was (15.26 ±6.15)days, and the time at left-neck was (11.14 ±5.28)days, the difference was statistically significant ( P<0.05 ) .The incidence of skin damage in treatment group and control group were 74.19%(23/31) and 87.10%(27/31) respectively, the difference was not statistically significant (P>0.05);thus difference of degree of skin damage between two groups was statistically significant ( P<0.05 ) .The incidence of moderate to severe pain in treatment group and control group were 35.48%and 70.97%respectively , the difference was statistically significant ( P<0.05 ) .Thirteen point zero four percent of patients in treatment group showed skin damage before total 20 Gy of irradiation, and 59.26%(16/27) of patients showed in the control group , the difference was statistically significant ( P<0.05 ) .Conclusion The frozen jiaweisanhuangtang can effectively prevent the occur-rence of acute radiation-induced neck skin damage , especially reduce the degree of skin damage , and it is worth fur-ther study .
Keywords：Radiation injuriesSkin damageRadiation protection agents
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1151-1153 )