Investigation on distribution of ABO and RhD blood type and gene frequencies of Zhuang minority in Nan-ning District of Guangxi
Abstract：Objective To investigate the distribution of RhD and ABO blood type and gene frequencies in Zhuang nationality in Nanning , Guangxi in order to provide the evidence for making reasonable blood management plan and prevention of ABO hemolytic disease of newborn .Methods The ABO and RhD blood groups of 4 527 unre-lated individuals were analyzed by randomized sampling .Results Blood type distribution showed O >B>A>AB, the genetic frequency included p (A)=0.1312, q(B)=0.1761 and r(O)=0.6927.The distribution of ABO blood type and genetic frequency met Hardy-Weinberg.Nationality index was 0.7636.The rate of positive RhD was 99.8012%,the rate of negative Rh ( D) was 0.1988% and the rate of d gene was 0.044587 .Conclusion Zhuang nationality in Nanning had low rate of negative Rh ( D) and distribution of ABO was characteristic of minority in this area, i.e.rate of O gene was high and rate of A gene was low .
Keywords：ABO blood typeRhD blood typeZhuang minorityGene frequencyHardy-Weinberg coincidence degree
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 1145-1147 )