Comparison of polylactic acid anti-adhesion gel and sodium hyaluronate in the prevention of postoperative in-testinal adhesion
LI Kun
LIU Ying-zi
GAO Hui-cong
Abstract：Objective To compare the effects of polylactic acid anti-adhesion gel and sodium hyaluronate in the prevention of postoperative intestinal adhesion , to guide the clinical use of drugs .Methods According to the se-lected anti adhesion drug , the patients were divided into polylactic acid anti-adhesion gel group and sodium hyalur-onate group , and were coated with polylactic acid anti-adhesion gel or sodium hyaluronate on the surgical wound at the end of operation and before closing abdomen .After operation , the time of temperature returning to normal , intestine ventilation time and the intestinal adhesion performance at 6 months after operation were observed .Results In all pa-tients, postoperative improvement was in good condition and no drug allergies , abscess, fistula and other adverse re-actions were found.Observation of postoperative 1 week showed patients′heating time, borborygmus recovery time, anal exhaust time , in polylactic acid anti-adhesion gel group were significantly better than those of sodium hyaluronate group(P<0.01).At 3 months or at 6 months after operation, the number of patients with intestinal adhesion per-formance in polylactic acid anti-adhesion gel group was significantly less than that in the sodium hyaluronate group ( P<0.05 ) .Conclusion Polylactic acid anti-adhesion gel and sodium hyaluronate in preventing postoperative intestinal adhesions have obvious effects , but the prevention effect of polylactic acid anti-adhesion gel is better than that of sodi-um hyaluronate .
Keywords：Intestinal adhesionPolylactic acid anti-adhesion gelSodium hyaluronatePrevention
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1071-1074 )