Correlation study among prehepatic fat thickness and insulin resistance in infertility patients with polycystic ovarian syndrome

doi:10.3969/j.issn.1674-3806.2013.11.01

Abstract：Objective To study the correlation between prehepatic fat thickness and insulin resistance inde-xes in infertility patients with polycystic ovarian syndrome ( PCOS) , and to provide theoretic basis for the clinical di-agnosis and treatment of infertility patients with PCOS .Methods The prehepatic fat thickness were detected by ultra-sonography, and the height, weight, waist circumstance, the circle of hip line in 91 infertility patients with PCOS were measured, and sex hormones, insulin and thyroid hormones were detected, while the blood glucose, lipids, liver and renal function indexes were detected also .The relation among prehepatic fat thickness and the above indexes were analyzed.Results There was a positive correlation among the prehepatic fat thickness and weight , body mass index (BMI), waist circumference, hip circumference(P<0.05), while no significant relation was found between prehe-patic fat thickness and height ( P>0.05 ) .There was a positive correlation between the prehepatic fat thickness and fasting insulin, serum sugar, uric acid, insulin resistance index(P<0.05).There was a negative correlation among the prehepatic fat thickness and high-density lipoprotein ( P<0.05 ) , while no significant relation was found among prehepatic fat thickness and sex hormones , thyroid hormones , total cholesterol , triglyceride , low density lipoprotein ( P>0.05 ) .Conclus ion There is a certain correlation between prehepatic fat thickness and insulin resistance inde -xes in infertility patients with PCOS , a complete diagnostic evaluation should be conducted in such patients before clinical diagnosis and treatment so as to improve their pregnancy rate and pregnant outcomes .