Combination use of oxidation-atomization inhalation and intravenous drop of ambroxol and their separate use in the treatment of children bronchial pneumonia:an analysis of therapeutic effect
Abstract：Objective To explore the therapeutic effect of combination use of oxidation-atomization inhala-tion and intravenous drop of ambroxol and their separate use in the treatment of children bronchial pneumonia .Meth-ods From September 2011 to March 2013 101 children with bronchial pneumonia , according to the admission time , were randomly divided into A , B, C groups.On the basis of comprehensive treatment , group A was treated with oxi-dation-atomization inhalation combined with intravenous drop of ambroxol , group B with oxidation-atomization inhala-tion of ambroxol , group C with intravenous drop of ambroxol .The comparison between 3 groups was performed of the total efficiency, the change of chest X-ray, days of hospitalization and symptom improvement time .Results (1) There was no statistically difference in total effective rate between 3 groups(P>0.05);(2)There was no statistically difference in clinical indexes(symptom improvement,day of hospitalization) between 3 groups(P>0.05);(3)After 7 days of treatment there was no statistically difference in change of chest X-ray between 3 groups(P>0.05);(4)No statistical significance among the 3 groups in changes WBC and CRP ( P>0.05 ) .But the number of cases of hs-CRP returned to normal in A group were more than B or C group ( P<0.05 ) .Conclusion The efficacy and the clinical index changes after treatment , WBC, chest X-ray and CRP of ambroxol oxidation-atomization inhalation combined with intravenous infusion of ambroxol in the treatment of children bronchial pneumonia is not superior to treatment with intravenous infusion or oxygen-driven inhalation of ambroxol , only there is advantage to restore hs-CRP, consider the combination of two routes of drug use should waste pharmaceutical sesource , increase the burden of patients , and waste of the nursing human resource .
Keywords：AmbroxolBronchial pneumoniaOxidation-atomization inhalation combined with intrave-nous dropOxidation-atomization inhalationIntravenous drop
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 945-948 )