The effect of combination of fluticasone propionate nasal spray and eucalyptol-linonene-pinene enteric soft capsule in the prevention of radioactive sinusitis
Abstract: Objective To perspectively observe the effect of combination of fluticasone propionate ( FP) na-sal spray and eucalyptol-linonene-pinene enteric soft capsule ( ELP) in the prevention of radioactive sinusitis in naso-pharyngeal carcinoma(NPC) patients.Methods Sixty NPC patients were divided into two groups by matched pair design from March 2009 to March 2011 in our department .Patients of the treating group received conventional radio-therapy(RT), chemotherapy(CT), FP nasal spray oral ELP.In control group,the patients received CT and RT a-lone.Six months after treatment the sinusitis was measured by using CT and MRI for the two groups .Results Fol-lowing up for six months ,the detected rates of sinusitis in the treating group was 40.0% and 76.7% in the control group, there were significantly difference between the two groups (P<0.01).The type and stage sinusitis: type 1, stage1 and type 1, stage2 accounted 41.67% respectively, type 1, stage3, 16.67% in the treating group;and 8.70%,56.52%,34.78%respectively in the control group .There were statistically significant difference between two groups(P<0.05).Conclusion Combination of FP nasal spray and ELP can reduce the incidence of radioactive si -nusitis and it is easy of use .
Keywords:Nasopharyngeal carcinomaRadiotherapySinusitis
Publication Date:2013-01-01
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:3( 769-771 )
