Effects of two kinds of solvents on skin test results of streptomycin prepared
ZHOU Mengwen
ZHANG Ling
ZHONG Honglan
Abstract：Objective To observe skin test results of streptomycin prepared using 2 different solvents: 0.9% sodium chloride injection and sterile water for injection. Methods One hundred tuberculosis patients, hospitalized between September 2013 and July 2014 in need of injecting streptomycin were selected.With their consent,their left forearms were administered with streptomycin prepared using saline as the solvent,while their right forearms were given streptomycin prepared using water for injection as the solvent.Their skin test results were observed 20 minutes later.Results The incidence of positive skin test results of streptomycin prepared in patients using water for injection as the solvent was significantly higher than that in patients using saline (χ2 =8,P <0.01).There were 1 6 patients with positive skin test of streptomycin prepared using water for injection as the solvent.There were 4 patients with negative skin test when using saline as the solvent.Conclusions There might be a high false positive rate when giving streptomycin prepared using the water for injection as the solvent,which is not recommended in clinical practice.
Keywords：StreptomycinSkin testWater for injectionSaline
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 386-387 )