To analyze the effect of rabeprazole combined with mosapride in the treatment of chronic laryngitis caused by gastroesophageal reflux
Deng Lina
Zhao Hongqin
Han Xue
Abstract：Objective To evaluate the efficacy of Rabeprazole+Mosapride in the treatment of chronic laryngitis(CL)caused by gastroesophageal reflux disease(GERD).Method A total of 76 patients with Gerd-induced CL from January 2019 to July 2022 were included and divided into control group(38 patients included,receiving rabeprazole)and observation group(38 patients included,receiving rabeprazole+Moxapride)according to random number table method.Intergroup response rate,laboratory indicators,reflux sign score(RFS),reflux symptom index(RSI),36 health survey summary form(SF-36),and adverse reactions were evaluated.Results(1)Compared with the control group(81.58%),the effective rate of the observation group(97.37%)was higher,P<0.05;(2)After 8 weeks of treatment,the laboratory indexes,RFS,RSI and SF-36 in the observation group were better,P<0.05;(3)There was no difference in adverse reactions between the observation group(7.89%)and the control group(10.53%),P>0.05.Conclusion Rabeprazole+Moxapride therapy for GerD-induced CL patients has significant efficacy,less adverse reactions,can relieve symptoms as soon as possible,improve laboratory indicators,and improve quality of life,which is worthy of promotion.
Keywords：RabeprazoleMoxaprideGastroesophageal refluxChronic laryngitis
Publication Date：2024-09-27
Online Publishing Date：2025-11-27(First online date of this platform, not the publication date of the document)
Pages：3( 47-49 )