Analysis of the efficacy and safety of low-dose He-Ne laser on radiation oral mucositis in patients with oral cancer

Lv Yougong

doi:10.19617/j.issn1001-1307.2023.06.26

Abstract：Objective To analyze the clinical effect and safety of low-dose helium-neon laser diagnosis and treatment of radiation oral mucositis in patients with oral cancer.Methods A study of patients with oral cancer radiation oral mucositis in our hospital from September 2019 to September 2021 was selected.128 cases were counted.They were divided into 2 groups and a control group(n=64),a study group(n=64),the control group took sham treatment,and the study group took low-dose helium-neon laser therapy to compare the efficacy of the two groups.Results ①Effective rate:The effective rate of the study group was higher than that of the control group,P＜0.05;②Pain score:The VAS score of the study group was lower than that of the control group at 7d,14d,and 21d after diagnosis and treatment,P＜0.05;③Adverse reactions:the adverse reaction rate of the study group There was no significant difference between the control group,P＞0.05;④Prognosis level:Compared with the control group,the healing rate of oral mucositis in the study group was significantly higher P＜0.05;⑤Sleep quality:The sleep quality factor scores of the study group were lower than those of the control group P＜0.05.Conclusion Low-dose helium-neon laser diagnosis and treatment of oral cancer patients with radiation-induced oral mucositis is effective.It is beneficial to reduce the severity of mucositis,promote inflammation healing,reduce pain,and have fewer adverse reactions.It has high application safety.